Insulin Sensitivity Factor (ISF) Calculator

Calculate how much one unit of insulin lowers your blood sugar. Essential for insulin-dependent diabetes patients to determine correction doses.

Calculator
Fill in the required information to get your results
Form Progress0%

Include long-acting (basal) and mealtime (bolus) insulin

How to Use This Calculator

Learn more about this topic and how it affects your health

Step 1: Find Your Total Daily Insulin

1

Add Up Your Basal Insulin

This is your long-acting insulin (like Lantus or Levemir)

2

Add Your Bolus Insulin

This is insulin you take with meals

3

Add Them Together

Example: 20 units basal + 15 units bolus = 35 total units

Step 2: Choose Your Correction Insulin

Rapid-Acting Insulin

Humalog, Novolog, Apidra, or Fiasp - works in 15 minutes

Regular Insulin

Humulin R or Novolin R - works in 30-60 minutes

Get Your ISF Result

See how much one unit of insulin drops your blood sugar

How the Calculator Works

Learn more about this topic and how it affects your health

The Math Behind It

1

For Rapid-Acting Insulin

We use the 1800 Rule: 1800 ÷ your total daily insulin

2

For Regular Insulin

We use the 1500 Rule: 1500 ÷ your total daily insulin

3

Get Your ISF Number

This tells you how much 1 unit drops your blood sugar

Real Example

Sarah's Situation

Sarah takes 30 units of insulin total per day

The Calculation

1800 ÷ 30 = 60 mg/dL per unit

What It Means

Each unit of insulin drops Sarah's blood sugar by 60 mg/dL

The Formulas

ISF = 1800 ÷ Total Daily Insulin

For rapid-acting insulin

ISF = 1500 ÷ Total Daily Insulin

For regular insulin

Understanding ISF

Learn more about this topic and how it affects your health

What is ISF?

ISF (Insulin Sensitivity Factor) is also called your "correction factor." It tells you how much one unit of insulin will lower your blood sugar.

Why It Matters:

  • • Helps you correct high blood sugar safely
  • • Prevents taking too much or too little insulin
  • • Keeps you from going low (hypoglycemia)

How to Use Your ISF

When your blood sugar is high, use your ISF to figure out how much insulin you need to bring it back to your target.

Quick Example:

  • • Your blood sugar is 200 mg/dL
  • • Your target is 100 mg/dL
  • • Difference: 100 mg/dL
  • • ISF is 50 → Take 2 units (100 ÷ 50 = 2)

Risk Factors

Learn more about this topic and how it affects your health

Things that can affect how sensitive you are to insulin

Things That Increase Sensitivity

These make insulin work BETTER (you need less):

  • Exercise and physical activity
  • Losing weight if overweight
  • Getting enough sleep

Things That Decrease Sensitivity

These make insulin work LESS (you need more):

  • Being sick or having an infection
  • Stress or not sleeping well
  • Hormones (like during periods or growth spurts)

Lifestyle Changes

Learn more about this topic and how it affects your health

Better Blood Sugar Control

Check Blood Sugar Regularly

Test before meals and 2 hours after to see how insulin is working

Keep a Diabetes Log

Write down blood sugar, insulin doses, and how you feel

Time Your Insulin Right

Rapid-acting: 15 min before eating. Regular: 30 min before

Healthy Habits

Stay Active

Exercise makes insulin work better, but check blood sugar first!

Eat Regular Meals

Don't skip meals - it makes blood sugar harder to control

Drink Water

Staying hydrated helps your body process glucose better

How to Get Accurate Readings

Learn more about this topic and how it affects your health

Testing Your ISF

  • Test when blood sugar is high and you haven't eaten for 4+ hours
  • Give a correction dose based on your calculated ISF
  • Wait 3-4 hours and check blood sugar again
  • See if you reached your target - adjust ISF if needed

Important Tips

  • Wash hands before testing (food on fingers affects results!)
  • Check meter and strips aren't expired
  • Don't correct if you took insulin in the last 3 hours
  • Your ISF might change over time - recheck every few months

When to Seek Emergency Care

Learn more about this topic and how it affects your health

Get help right away if you have these symptoms:

Severe Low Blood Sugar (Hypoglycemia):

  • Can't think clearly or feeling confused
  • Shaking badly or having seizures
  • Can't wake up or pass out
  • Blood sugar below 55 mg/dL and not rising

Severe High Blood Sugar (DKA - Diabetic Ketoacidosis):

  • Throwing up and can't keep fluids down
  • Breathing really fast or having trouble breathing
  • Fruity smell on breath
  • Blood sugar over 300 mg/dL with ketones

Call Your Doctor Soon If:

  • Blood sugar stays high even with correction doses
  • You're getting low blood sugar a lot
  • Your ISF doesn't seem to be working right
Disclosure: As an Amazon Associate, we earn from qualifying purchases. When you click on product links, we may receive a commission at no additional cost to you.